| 1922-04-26 | Witton Albion v Connah'S Quay & Shotton | 1-1 | | 1921-22 | EYRES |
| 1922-04-22 | Nantwich v Witton Albion | 1-1 | | 1921-22 | REYNOLDS |
| 1922-04-17 | Witton Albion v Stockport County Reserves | 7-0 | | 1921-22 | HOWARD, HOWARD, EYRES, EYRES, REYNOLDS, TATTUM, GREGORY |
| 1922-04-15 | Witton Albion v Winsford United | 3-0 | | 1921-22 | REYNOLDS, REYNOLDS, HOWARD |
| 1922-04-14 | Northwich Victoria v Witton Albion | 2-2 | | 1921-22 | FLETCHER, HOWARD (p) |
| 1922-04-08 | Witton Albion v Mossley | 5-3 | | 1921-22 | EYRES, EYRES, EYRES, EYRES, HOWARD |
| 1922-04-01 | Ellesmere Port Cement v Witton Albion | 0-2 | CSC S/F | 1921-22 | HOWARD, FLETCHER |
| 1922-03-29 | Winsford United v Witton Albion | 2-1 | CLC 3rd. Rep. | 1921-22 | RYAN |
| 1922-03-25 | Witton Albion v Chester | 4-0 | | 1921-22 | HOWARD, EYRES, REYNOLDS, TATTUM |
| 1922-03-22 | Winsford United v Witton Albion | 1-1 | CLC 2nd. Rep. | 1921-22 | HOWARD |
| 1922-03-18 | Winsford United v Witton Albion | 0-2 | CSC 2 | 1921-22 | HOWARD, HOWARD |
| 1922-03-11 | Witton Albion v Winsford United | 1-1 | CLC 2 Rep. | 1921-22 | RIGBY |
| 1922-03-04 | Sandbach Ramblers v Witton Albion | 0-0 | | 1921-22 | |
| 1922-02-25 | Witton Albion v Ashton National | 2-1 | | 1921-22 | EYRES, EYRES |
| 1922-02-22 | Witton Albion v Stockport County | 2-0 | CSC 1 Rep. | 1921-22 | HOWARD (p), TATTUM |
| 1922-02-18 | Mossley v Witton Albion | 0-1 | | 1921-22 | HOWARTH |
| 1922-02-11 | Witton Albion v Stockport County | 2-2 | CSC 1 | 1921-22 | HOWARD (p), TATTUM |
| 1922-01-28 | Witton Albion v Runcorn | 5-1 | | 1921-22 | HOWARD, HOWARD, HOWARD, HOWARD (p), EYRES |
| 1922-01-21 | Altrincham v Witton Albion | 7-2 | | 1921-22 | REYNOLDS, EYRES (p) |
| 1922-01-14 | Stalybridge Celtic Reserves v Witton Albion | 1-0 | | 1921-22 | |
| 1922-01-07 | Witton Albion v Sandbach Ramblers | 3-1 | CSC 4q. | 1921-22 | EYRES, SEDDON, BENNETT |
| 1922-01-02 | Witton Albion v Macclesfield | 3-1 | | 1921-22 | SEDDON, SEDDON, HOWARD |
| 1921-12-31 | Saltney Athletic v Witton Albion | 7-0 | | 1921-22 | |
| 1921-12-27 | Witton Albion v Saltney Athletic | 3-1 | | 1921-22 | REYNOLDS, EYRES, SPENCER (p) |
| 1921-12-26 | Witton Albion v Northwich Victoria | 1-1 | | 1921-22 | REYNOLDS |
| 1921-12-24 | Congleton Town v Witton Albion | 3-2 | | 1921-22 | EYRES, EYRES |
| 1921-12-17 | Runcorn v Witton Albion | 0-0 | | 1921-22 | |
| 1921-12-10 | Witton Albion v Altrincham | 2-0 | | 1921-22 | HOWARD, EYRES |
| 1921-12-03 | Stockport County Reserves v Witton Albion | 1-2 | | 1921-22 | WATSON, EYRES (p) |
| 1921-11-26 | Witton Albion v Tranmere Rovers Reserves | 3-0 | | 1921-22 | HOWARD, HOWARD, REYNOLDS |
| 1921-11-19 | Tranmere Rovers Reserves v Witton Albion | 3-4 | | 1921-22 | EYRES, EYRES, EYRES, REYNOLDS |
| 1921-11-12 | Witton Albion v Stalybridge Celtic Reserves | 6-2 | | 1921-22 | EYRES, EYRES, EYRES, WATSON, HOWARD, REYNOLDS |
| 1921-11-05 | Ellesmere Port Cement v Witton Albion | 4-2 | | 1921-22 | HOWARD, REYNOLDS |
| 1921-10-29 | Witton Albion v Whitchurch | 0-1 | | 1921-22 | |
| 1921-10-22 | Whitchurch v Witton Albion | 0-2 | | 1921-22 | HOWARD, EYRES |
| 1921-10-15 | Witton Albion v Crewe Alexandra Reserves | 5-0 | | 1921-22 | EYRES, EYRES, EYRES, HOWARD, WATSON |
| 1921-10-08 | Crewe Alexandra Reserves v Witton Albion | 0-1 | | 1921-22 | EYRES |
| 1921-10-03 | Macclesfield v Witton Albion | 3-0 | | 1921-22 | |
| 1921-10-01 | Witton Albion v Nantwich | 1-1 | | 1921-22 | EYRES |
| 1921-09-28 | Winsford United v Witton Albion | 1-1 | CLC 2 | 1921-22 | HOWARD |
| 1921-09-24 | Nantwich v Witton Albion | 4-2 | FAC Pr. | 1921-22 | EYRES, EYRES |
| 1921-09-17 | Witton Albion v Congleton Town | 0-1 | | 1921-22 | |
| 1921-09-10 | Ashton National v Witton Albion | 3-0 | | 1921-22 | |
| 1921-09-07 | Witton Albion v Northwich Victoria | 3-0 | CLC 1 | 1921-22 | HOWARD (p), SEDDON, EYRES |
| 1921-09-03 | Witton Albion v Sandbach Ramblers | 2-1 | | 1921-22 | HOWARD, REYNOLDS |
| 1921-08-27 | Winsford United v Witton Albion | 0-2 | | 1921-22 | HOWARD, BROCKBANK |
| 1921-05-07 | Witton Albion v Ashton National | 1-0 | Altrincham SC F | 1920-21 | Not Known |
| 1921-04-30 | Witton Albion v Runcorn | 1-0 | | 1920-21 | SEDDON |
| 1921-04-23 | Witton Albion v Altrincham | 1-0 | Altrincham SC S/F | 1920-21 | Not Known |
| 1921-04-16 | Nantwich v Witton Albion | 3-0 | | 1920-21 | |
